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The regulations entitled "The Dangerous Substances and Preparations (Nickel) (Safety) Regulations 2005" clearly require that any finding component that pierces the skin may not release more than .2 micrograms of nickel per cubic centimeter per week, and that no other jewelry component release no more than .5 micrograms of nickel per cubic centimeter per week. Note that these regulations do not prohibit the use of nickel in jewelry components, but rather limits the amount to which a person may be exposed.
Nickel exposure is tested under BS EN12472 and BS EN 1811:1999. The first of these separate tests replicates two years of wear under normal use, and the second tests for subsequent exposure to nickel.